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Notice of Bioinformatics Course Selection

发布日期:2019-12-25 发表者:陈治国 浏览次数:


Notice of Bioinformatics Course Selection

(Spring semester, 2020)


Bioinformatics course in English will be offered from April 20th to June 19th 2020, on the following schedule: the last two classes on Monday afternoons and the last two classes on Friday afternoons AT YIFU building C619.

If you are interested, please Email Dr. Liu (liurong116@mail.hzau.edu.cn) your name, student ID, major and affiliation BEFORE January 15th, 2020.


Best regards,


Rong Liu

College of Informatics in HZAU

Email: liurong116@mail.hzau.edu.cn

Homepage: /info/1093/3004.htm

Bioinformatics Teaching Plan

College of Informatics, HZAU

Available in spring of 2020


Description: This course is based on the Bioinformatics course offered to senior undergraduate students and graduate students. It is an introduction to bioinformatics, which is loosely defined as the intersection between the fields of molecular biology and computer science. This course, which is geared for biologists, consists of eight lectures describing major topics in bioinformatics that will be covered in seven weeks. In each week, one or two lectures (around 1.5 hrs) will be offered, followed by one lab session, which provides an opportunity to use and experiment on bioinformatics software and databases in current genomic and bioinformatics-based research. In the last week of this course, graduate students will present recent progress in bioinformatics for selected topics.

Course prerequisite: Students should have taken molecular biology and one introductory computer science course.

Text book: None. Course slides and reading materials will be provided to students.


Course outline (eight weeks)

Week 1

Lecture 1: What is bioinformatics? History and future of genetics and genomics

Lecture 2: Biological data models and bioinformatics databases

Lab 1: Linux OS, vi text editor, NCBI databases, Ensemble, UCSC genome browser


Week 2 and Week 3

Lecture 3: Pairwise sequence alignment

Lecture 4: Sequence alignment and database searching

Lab 2-3: Perl programming: syntax, variables, scalar, array; dotplot, BLAST searches, local


Week 4 and Week 5

Lecture 5: Gene finding and genome annotation

Lecture 6: Multiple sequence alignment and molecular evolution

Lab 4-5: Perl programming: string, numbers, hash, logical and relational operators; ORF finder, GeneWise, clustalw, jalview


Week 6 and Week 7

Lecture 7: Phylogenetic analysis

Lecture 8: Functional analysis of proteins

Lab 6-7: Perl programming: regular expression, file handles, subroutine; MEGA5, InterProScan, DAVID, PDB


Week 8

Current topics in bioinformatics 1: Student presentations

Current topics in bioinformatics 2: Student presentations

Final examination


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